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Resources

Access resources for every step of the treatment journey

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Genetic testing

Videos for HCPs

HCP resources

Patient resources

GENETIC TESTING

If you suspect your patient may have a PI, genetic testing that includes APDS can help inform a timely diagnosis.

Sponsored genetic testing and genetic counseling are available for eligible patients and their families, regardless of insurance coverage or financial need.

Learn more about a sponsored genetic testing option.

Order a genetic test

Eligibility criteria apply.

Locate a clinician who understands APDS

APDS is a rare, genetic inborn error of immunity (IEI), and as a result, a limited number of clinicians have had first-hand experience with APDS.

Find medical professionals who have experience diagnosing and managing APDS near you.

Search now

VIDEOS FOR HCPs

Watch these educational videos

5:41

Joenja’s mechanism of action

Watch Joenja in action and gain a clearer understanding of how Joenja targets the underlying immune defect in APDS.

More Videos

51:54

Learn about APDS and Joenja

Dr Hartog, a leading allergy and immunology specialist and clinical expert on APDS, discusses a real life patient cas…

58:29

Joenja targeting the mechanics of APDS

Dr Mehta, a hematologist/oncologist and leading clinical expert on APDS, explains how Joenja targets the mechanics o…

HCP RESOURCES

Resources for you and your office

An overview of Joenja for HCPs

A comprehensive brochure providing a brief introduction to APDS and a detailed description of Joenja that includes an explanation of how Joenja works, the clinical data on the efficacy and safety of Joenja, and Joenja dosing and administration information.

Download overview

Joenja patient case vignettes

Explore patients’ experiences with Joenja to gain insights about the treatment and learn how it impacted patients with APDS who were observed for 6 years.

Download vignettes

Get in touch

Sign up for emails to get the latest news and stay up to date on everything Joenja.

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PATIENT RESOURCES

Resources for your patients

Patient brochure

Learn more about Joenja results and dosing.

Download brochure

Patient enrollment form (APDS Assist)

Complete the enrollment form below and submit it to APDS Assist.

Download form

Full list of patient resources available on Joenja.com

Help your patients throughout their treatment journey by sharing helpful resources like the administration guide and Joenja brochure.

View all patient resources

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Advocacy groups

Patients with APDS may find it helpful to know there are hundreds of other people in the US living with APDS. Click on each logo below to learn about patient advocacy groups that are dedicated to supporting the APDS community.

Connect with Joenja

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APDS Assist

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APDS, activated PI3K delta syndrome.

Indications and Usage

JOENJA® (leniolisib) is a kinase inhibitor indicated for the treatment of activated phosphoinositide 3-kinase delta (PI3Kδ) syndrome (APDS) in adult and pediatric patients 12 years of age and older.

Indications and Usage

JOENJA® (leniolisib) is a kinase inhibitor indicated for the treatment of activated phosphoinositide 3-kinase delta (PI3Kδ) syndrome (APDS) in adult and pediatric patients 12 years of age and older.

Important Safety Information

Verify pregnancy status in females of reproductive potential prior to initiating treatment with JOENJA.

JOENJA may cause fetal harm when administered to a pregnant woman. Advise patients of the potential risk to a fetus and to use highly effective methods of contraception during treatment with JOENJA and for 1 week after the last dose. Additionally, advise women not to breastfeed during treatment with JOENJA and for 1 week after the last dose.

Live, attenuated vaccinations may be less effective if administered during JOENJA treatment.

JOENJA may cause hypersensitivity reaction(s), including anaphylaxis. Advise patients to discontinue JOENJA and to seek immediate medical attention if they develop any signs and symptoms of serious allergic reactions.

Use of JOENJA in patients with moderate to severe hepatic impairment is not recommended. There is no recommended dosage for patients weighing less than 45 kg.

Avoid co-administration of JOENJA with other medications known to be strong CYP3A4 inhibitors, strong or moderate CYP3A4 inducers, or BCRP, OATP1B1, and OATP1B3 substrates.

The most common adverse reactions (incidence >10%) were headache, sinusitis, atopic dermatitis, and weight gain.

Seven (33%) patients receiving JOENJA developed an absolute neutrophil count (ANC) between 500 and 1500 cells/microL. No patients developed an ANC <500 cells/microL and there were no reports of infection associated with neutropenia.

Before prescribing JOENJA, please read the full Prescribing Information.

What Is APDS?

How Joenja Works

Joenja Results & Safety

Joenja Results
(Adolescents & Adults 12+) Joenja Results
(for Children Ages 4-11)

Dosing & Administration

Access & Resources

APDS Assist Resources

Request a Rep

Full Prescribing Information Contact Us Privacy Policy Terms of Use Cookie Policy

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